Acyclovir may improve the prognosis of patients with an elevated HSV viral load during ventilator-associated pneumonia not responding to antibiotic treatment.

Impact of acyclovir use on survival of patients with ventilator-associated pneumonia and high load herpes simplex virus replication.

  • Schuierer L. et al.
  • Rédigé par : Dr Olivier Leroy
Herpes simplex virus (HSV) replication can be detected in the respiratory secretions of a high proportion of ventilated intensive care unit (ICU) patients. It appears to be associated with increased mortality. This could be modified by treatment with acyclovir but the results are controversial, hence this study. Methods Retrospective study conducted in Germany between 2013 ...
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