Lefamulin versus moxifloxacin for the treatment of community-acquired bacterial pneumonia. Results of a phase III trial. ( File TM. et al. )

Efficacy and Safety of Intravenous-to-oral Lefamulin, a Pleuromutilin Antibiotic, for the Treatment of Community-acquired Bacterial Pneumonia: The Phase III Lefamulin Evaluation Against Pneumonia (LEAP 1) Trial.

| Dr Jean-Pierre Bru

Lefamulin is a pleuromutilin antibiotic. Its name comes from the pleuromutilin-producing fungus Pleurotus mutilus. Previous pleuromutilin are already used : … Suite  

Does Colistin-Meropenem combination therapy reduce the emergence of colistin resistance vs. Colistin monotherapy? ( Dickstein Y. et al. & AIDA study group. )

Colistin Resistance Development Following Colistin-Meropenem Combination Therapy vs. Colistin Monotherapy in Patients with Infections Caused by Carbapenem-Resistant Organisms.

| Dr Jean-Pierre Bru

Colistin is one of a limited number of options for the treatment of carbapenem-resistant Gram-negative bacteria. A previously published randomized … Suite