Anidulafungin and Micafungin concentrations in Cerebrospinal Fluid and in Cerebral Cortex.

As penetration of caspofungin into the human central nervous system (CNS) is known to be limited, this study aimed to quantified anidulafungin and micafungin in cerebrospinal fluid (CSF) of critically ill patients and in cerebral cortex of deceased. Methods Anidulafungin and micafungin were quantified in cerebrospinal fluid (CSF) of critically ill adults and in cerebral cor...