Ceftazidime-avibactam: monotherapy or combination therapy to treat carbapenem resistant gram-negative infections ?

Ceftazidime/avibactam, display in vitro activity against strains producing class-A-carbapenemases, including Klebsiella pneumoniae (KPC), as well as some class-D-carbapenemases, Some recent studies, although limited in number, have reported encouraging results in the treatment these infections. The aim of this study was to compare the efficacy of ceftazidime/avibactam used in monotherapy or in...