Does 1 or 2 g daily of Ceftriaxone affects clinical outcome in ICU patients?
Comparison of Clinical Outcomes among Intensive Care Unit Patients Receiving One or Two Grams of Ceftriaxone Daily.
Rédigé par : Dr Jean-Pierre Bru
Pharmacokinetic data suggest ICU patients with sepsis, including those with hypoalbuminemia, may experience ceftriaxone underexposure. But clinical outcomes data are lacking. The objective of this study was to determine the impact of ceftriaxone dosing (1 g/d compared to 2 g/d) on clinical outcomes among ICU patients without central nervous system (CNS) infection.
Methods
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