Does Colistin-Meropenem combination therapy reduce the emergence of colistin resistance vs. Colistin monotherapy?

Colistin Resistance Development Following Colistin-Meropenem Combination Therapy vs. Colistin Monotherapy in Patients with Infections Caused by Carbapenem-Resistant Organisms.

  • Dickstein Y. et al. & AIDA study group.
  • Rédigé par : Dr Jean-Pierre Bru
Colistin is one of a limited number of options for the treatment of carbapenem-resistant Gram-negative bacteria. A previously published randomized controlled trial (RCT) compared colistin monotherapy with colistin-meropenem combination for the treatment of severe infections caused by carbapenem-resistant, colistin-susceptible Gram-negative bacteria. No difference was found in clinical failure o...
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