In units with high rates of resistance empirical use of colistin in the treatment of late ventilator-associated pneumonia cannot be recommended.
Colistin versus meropenem in the empirical treatment of ventilator-associated pneumonia (Magic Bullet study): an investigator-driven, open-label, randomized, noninferiority controlled trial.
Rédigé par : Dr Olivier Leroy
Multidrug-resistant gram-negative bacilli (MDR-GNB), including Pseudomonas aeruginosa, Acinetobacter baumannii, and extended-spectrum beta-lactamase (ESBL)-producing or carbapenemase-producing Enterobacteriaceae, are currently the pathogens most frequently isolated from patients with late VAP in some countries. The management of patients having VAP caused by suspected or proven MDR-GNB remains ...
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