It’s time for oral step-down therapy for the treatment of Infective Endocarditis.

Evaluation of a Paradigm Shift From Intravenous Antibiotics to Oral Step-Down Therapy for the Treatment of Infective Endocarditis. A Narrative Review.

  • Spellberg B. et al.
  • Rédigé par : Dr Jean-Pierre Bru
Most of the current guidelines for the management of infective endocarditis (IE) recommend prolonged intravenous antibiotic courses without any oral switch. The aim of this work was to evaluate the medical literature to determine whether there was compelling evidence for the superiority of prolonged intravenous therapy vs oral step-down therapy for IE. Methods Review of the...
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