Latent tuberculosis infection: the 4-month course of rifampicin is safer than the 9-month course of isoniazid

Adverse events in adults with latent tuberculosis infection receiving daily rifampicin or isoniazid: post-hoc safety analysis of two randomised controlled trials

  • Jonathon R Campbellet al
  • Rédigé par : Pr Pierre Tattevin
Different regimens have similar efficacy for the treatment of latent tuberculosis infection (LTI), including 3 months of isoniazid (INH)/rifampicin (RMP), 4 months of RMP, and 9 months of INH. Hence, tolerability is a major criteria to define the optimal regimen. Results In this post-hoc analysis of 2 open-label randomized trials comparing 4 months of RMP and 9 months of ...
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