Pulmonary diffusion of dalbavancin could allow its use in the treatment of pneumonia
Epithelial Lining Fluid and Plasma Concentrations of Dalbavancin in Healthy Adults after a Single 1,500-Milligram Infusion.
Rédigé par : Dr Olivier Leroy
Pneumonia is frequently caused by gram-positive cocci including S. aureus and S. pneumoniae. Dalbavancin is effective against these pathogens and appears unaffected by the presence of surfactant. Experimental studies suggest efficacy of this molecule in pneumonia models. Nevertheless, the effectiveness of an antibiotic in the treatment of lower respiratory tract infections depends on its abilit...
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