In patients with septic shock, it is likely that meropenem should be used with a loading dose and higher doses than recommended. ( Kothekar AT, et al. )
Clinical pharmacokinetics of 3 h extended infusion of meropenem in adult patients with severe sepsis and septic shock: implications for empirical therapy against Gram negative bacteria
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Meropenem break points for enterobacteriacea, P. aeruginosa and A. baumannii, range from 2 to 8 mg/l. The usual recommended doses … Suite