Which pharmacodynamics targets for β-lactam in Gram-negative bloodstream infections in the critically ill ?
β-Lactam pharmacodynamics in Gram-negative bloodstream infections in the critically ill.
Rédigé par : Dr Jean-Pierre Bru
The objective was to better determine the β-lactam exposure associated with positive clinical outcomes for Gram-negative blood stream infection (BSI) in critically ill patients.
Methods
Patients admited in ICU with monomicrobial Gram-negative blood stream infections (BSI) treated with β-lactams were included.
The ratio unbound β-lactam antibiotic concentration at trough to...
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