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Treatment of Carbapenem-Resistant Enterobacterales: guidelines from IDSA. ( Pranita D. Tamma and al. )

Infectious Diseases Society of America Antimicrobial Resistant Treatment Guidance: Gram-Negative Bacterial Infections A Focus on Extended-Spectrum β-lactamase Producing Enterobacterales (ESBL-E), Carbapenem-Resistant Enterobacterales (CRE), and Pseudomonas aeruginosa with Difficult-to-Treat Resistance (DTR-P. aeruginosa).

24 sept | Dr Jean-Pierre Bru

The IDSA publishes guidelines for the treatment of infections due to Extended-Spectrum β-lactamase Producing Enterobacterales (ESBL-E), Carbapenem-Resistant Enterobacterales (CRE), and Pseudomonas … Suite

Suboptimal dosing of fluconazole in critically ill patients. ( Eline W Muilwijk et al. )

Suboptimal dosing of fluconazole in critically ill patients – time to rethink dosing.

22 sept | Dr Jean-Pierre-Bru

Fluconazole is frequently used for treatment of invasive Candida infections in critically ill patients as primary therapy or early “step … Suite

Mycoplasma genitalium infection: efficacy of resistance-guided antimicrobial therapy using doxycycline-moxifloxacin and doxycycline-2.5g azithromycin. ( Duygu Durukan et al. )

Resistance-guided antimicrobial therapy using doxycycline-moxifloxacin and doxycycline-2.5g azithromycin for the treatment of Mycoplasma genitalium infection: efficacy and tolerability.

15 sept | Dr Jean-Pierre Bru

Mycoplasma genitalium (MG) is highly prone to developing antimicrobial resistance. Macrolide-resistance exceeds 50% in many regions and quinolone-resistance is increasing. … Suite

Which duration of antibiotic therapy in central venous catheter-related bloodstream infection due to Gram-negative bacilli? ( María Ruiz-Ruigómez et al. )

Impact of duration of antibiotic therapy in central venous catheter-related bloodstream infection due to Gram-negative bacilli?

10 sept | Dr Jean-Pierre Bru

Current guidelines recommend antibiotic treatment for at least 7–14 days, although the supporting evidence is limited. Results of previous studies … Suite

Place of FDG-PET/CT in the management of S. aureus blood stream infections. ( Nesrin Ghanem-Zoubi et al. )

Integration of FDG-PET/CT in the diagnostic workup for Staphylococcus aureus bacteremia: a prospective interventional matched-cohort study.

03 sept | Dr Jean-Pierre Bru

The aim of the study was to assess the role of integrating FDG-PET/CT in the management of S. aureus blood … Suite

Which doses for gentamicin in patients with obesity and renal dysfunction? ( Cornelis Smit et al. )

Dose recommendations for gentamicin in the real-world obese population with varying body weight and renal (dys)function.

01 sept | Dr Jean-Pierre Bru

The aim of this study was to characterize the pharmacokinetics of gentamicin in real-world obese patients, including those with renal … Suite

Treatment duration of uncomplicated Gram-negative bacteremia : a randomized controlled trial ( Elodie von Dach, et al. )

Effect of C-Reactive Protein–Guided Antibiotic Treatment Duration, 7-Day Treatment, or 14-Day Treatment on 30-Day Clinical Failure Rate in Patients With Uncomplicated Gram-Negative Bacteremia : A Randomized Clinical Trial.

27 août | Pr Pierre Tattevin

To reduce the duration of antibiotic (ATB) treatment for common infections is one of the most promising interventions to reduce … Suite

Honey, efficient for symptomatic relief in upper respiratory tract infections could be an alternative to antibiotics. ( Abuelgasim H, et al )

Effectiveness of honey for symptomatic relief in upper respiratory tract infections: a systematic review and meta-analysis

25 août | Dr Jean Pierre Bru

The use of antibiotics for upper respiratory tract infections (URTIs) is an important problem. They are ineffective, and contribute to … Suite

Cefepime in critically ill patients: probability of target attainment. ( Mohammad H Al-Shaer et al. )

Population pharmacokinetics and target attainment of cefepime in critically ill patients and guidance for initial dosing.

09 juil | Dr Jean-Pierre Bru

This study aimed to investigate the cefepime regimens associated with the optimal exposure in critically ill patients. Methods Two datasets … Suite

Follow-up blood cultures are associated with improved outcome of patients with gram-negative bloodstream infections. ( Maskarinec SA et al. / Giannella M. et al )

Positive follow-up blood cultures identify high mortality risk Among patients with gram negative bacteremia.⁽¹⁾ / Follow-up blood cultures are associated with improved outcome of patients with gram-negative bloodstream infections: retrospective observational cohort study. ⁽²⁾

02 juil | Dr Jean-Pierre Bru

Follow up blood cultures (FUBC) are recommended in the management of Staphylococcus aureus bacteremia, endocarditis, and candidemia but are not … Suite