Critically ill - info-atbvac

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Suboptimal dosing of fluconazole in critically ill patients. ( Eline W Muilwijk et al. )

Suboptimal dosing of fluconazole in critically ill patients – time to rethink dosing.

22 sept | Dr Jean-Pierre-Bru

Fluconazole is frequently used for treatment of invasive Candida infections in critically ill patients as primary therapy or early “step … Suite

Anidulafungin and Micafungin concentrations in Cerebrospinal Fluid and in Cerebral Cortex. ( Jana Marx et al. )

Anidulafungin and Micafungin concentrations in Cerebrospinal Fluid and in Cerebral Cortex.

05 mai | Dr Jean-Pierre Bru

As penetration of caspofungin into the human central nervous system (CNS) is known to be limited, this study aimed to … Suite

Is it time to administer ceftriaxone as continuous infusion in critically ill patients? ( Leegwater E. et al. )

Population pharmacokinetics of ceftriaxone administered as continuous or intermittent infusion in critically ill patients.

31 mar | Dr Jean-Pierre Bru

Ceftriaxone has a long half-life of approximately 8.5 h, owing a once daily administration. But in critically ill patients, the … Suite

Continuous infusion of cefotaxime lead to better PK target attainment versus intermittent infusion in critically ill patients. ( Aardema H. and al. )

Continuous versus intermittent infusion of cefotaxime in critically ill patients: a randomized controlled trial comparing plasma concentrations.

16 jan | Dr Jean-Pierre Bru

To date, only two observational studies on cefotaxime dosing in critical care populations are available, none of them compared continuous … Suite